岳源,男,副教授,博士研究生,毕业于武汉大学生物化学与分子生物学专业。
美国明尼苏达双城大学博士后。曾获2015年医学部突出贡献奖、2015年武汉市黄鹤英才。
研究方向:
神经退行性疾病及多发性硬化症相关机制研究。
科研项目成果:
1.论文:
①Yue Y, Wu S, Zhang H, et al. Characterization and hepatoprotective effect of polysaccharides from Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex HF Chou sarcocarp[J]. Food and Chemical Toxicology,2014, 74: 76-84. (IF:6.023; 1 区)
②Yue Y, Wu S, Li Z, et al. Wild jujube polysaccharides protect against experimental inflammatory bowel disease by enabling enhanced intestinal barrier function[J]. Food & function, 2015, 6(8):2568-2577. (IF:5.396;1 区)
③Yue Y, Stone S, Lin W. Role of nuclear factor κB in multiple sclerosis and experimental autoimmune encephalomyelitis[J]. Neural regeneration research, 2018, 13(9): 1507. (IF:5.9; 2 区)
④Yue Y, Milos Stanojlovic, Yifeng Lin, Lin W. Oligodendrocyte-specific ATF4 inactivation does not influence the development of EAE. J Neuroinflammation. 2019 Feb 1;16(1):23. (IF:9.3; 1 区)
⑤Wu S*, Yue Y*, Li J, et al. Procyanidin B2 attenuates neurological deficits and blood–brain barrier disruption in a rat model of cerebral ischemia[J]. Molecular nutrition & food research, 2015, 59(10):1930-1941. (Co-first author; IF: 5.914; 1 区)
⑥Wu S*, Yue Y*, Peng A, et al. Myricetin ameliorates brain injury and neurological deficits via Nrf2 activation after experimental stroke in middle-aged rats[J]. Food & function, 2016, 7(6): 2624-2634.(Co-first author; IF: 5.396; 1 区)
⑦Stone S*, Yue Y*, Stanojlovic M, et al. Neuron-specific PERK inactivation exacerbates neurodegeneration during experimental autoimmune encephalomyelitis[J]. JCI insight, 2019,4(2).(Co-first author; IF:8.315;1 区;)
⑧Yue Y, Wang J, Tian J. Glycyrrhizic acid promote remyelination after peripheral nerve injury by reducing NF-κB activation. Neurosci Lett. 2024 Nov 20;843:138009.
2.项目:
①Rho 激酶作为炎症性肠病防治新靶标的研究,国家自然基金面上项目:81273523;标书撰写,主要参与者。
②设计并完成因卡膦酸二钠抗肺炎骨转移研究
③抗结核一类新药 YF-49-92 临床前药效学研究。
④肝动脉介入米箔对原发性肝癌的抗癌效果研究。
3.专利:
①202410897070.5;一种用于免疫细胞玻璃化的冻存液及其应用.岳源,方宏亮,田阳,韩洪坤,许晓泉
②202430617203.X;包装盒(盐酸佐利替尼片)。周晔,翁雪舟,方宏亮,岳源
③ZL 2012 1 0287615.8; Application of 3-amino-1-propanesulfonic acid and its derivative in medicine preparation for treating cerebral stroke. Ding Hong, Wu shuangchan, Yue Yuan
④ ZL 2012 1 0534121.5; Glycine-L-cysteine-homotaurine tripeptide and application thereof. Ding Hong, Wu shuangchan, Yue Yuan
⑤ZL 2012 1 0090100.9; A polysaccharide composite and its preparation method and uses. Ding Hong, Yue Yuan, Wu Shuangchan, Yang Ge
⑥ZL 2013 2 0327863.0; Chromatographic column. Ding Hong, Yue Yuan, Wu Shuangchan, Li Jian
⑦ZL 2013 1 0396559.6; Chitosan and tripeptide composition as well as preparation method and application thereof. Ding Hong, Yue Yuan, Wu Shuangchan
⑧ZL 2015 1 0003889.3; GAOH derivative and medical application thereof. Ding Hong, Yue Yuan, Wu Shuangchan, Li Jian
⑨ ZL 2014 1 0798725.X; Application of chimonanthus nitens extract in preparation of medicines for treating neurological diseases and myasthenia. Ding Hong, Li Xiaofei, Wu shuangchan, Yue Yuan.
⑩ZL 2015 1 0569359.5; Cysteine-high-taurine dipeptide, derivative of cysteine-high-taurine dipeptide and medicine purpose of cysteine-high-taurine dipeptide and derivative of cysteine-high-taurinedipeptide. Tong Jing, Ding Hong, Wu shuangchan, Li Jian, Yue Yuan